The IE-251A is a moderately priced intracellular electrometer complete with current passing capability and incorporating the same basic design as the more costly IE-210.
The IE-251 is a low cost version of our popular IE-210 intracellular amplifier. The important features required for low noise, drift free recording from glass microelectrodes have been retained in this lower cost model. The IE-251A is easy to use and is an excellent choice for the budget-conscious researcher or student teaching lab. It features a very small active headstage, essentially the same as used with the more costly IE-210. Epoxy-sealed construction affords maximum resistance to saline corrosion. Its small size and low mass permit easy mounting in a micropositioner. The electrode holder supplied connects directly to the probe input.
The injection circuitry of the IE-251A allows simultaneous stimulation and recording through microelectrode resistances up to 1000 MΩ in two ranges. Voltages at the Stimulus Input are converted to constant currents applied to the electrode. The steady state and transient components of the current injection artifact are nulled with the DC and transient balance controls. The corrected signal is viewed at the single-ended bridge output. Electrode resistance is read from the DC balance ten-turn dial.
Two visual indicators call attention to overload conditions:
The IE-251A is supplied with a probe. However, an electrode holder must be purchased separately based on your glass outer diameter. Also, specify line operating voltage if other than 100-130 VAC. Typical electrode holder options are listed below with pricing information.
The headstage of the instrument can be connected to the E Series electrode holder with a straight body. The HEKA data acquisition system can be utilized to record the data.
Amplifier | Input Impedance | 1011 Ω shunted by 0.5 pF |
---|---|---|
Noise Level | (0.1 Hz to 10 kHz)* | |
25 µV p-p input shorted |
||
250 µV p-p, 20 MΩ at input |
||
Output Resistance | 100 Ω | |
Gains | x1, x10 | |
Rise Time (10 to 90%) | 10 µs measured with 20 MΩ resistor | |
Capacity Compensation | 0 to 50 pF | |
Probe Input Voltage Range | ±1 V | |
DC Positioning Range | ±200 mV referred to input | |
Leakage Current | Adjustable to zero | |
Electrode Test | 1 mV/MO | |
Buzz | Amplitude variable | 0-15 V |
Frequency variable | 100 Hz to 10 kHz | |
Current Injection | Bridge Balance Ranges | 0 - 100 MΩ and 0 - 1000 MΩ |
Current Injection Limit | ±1 V divided by electrode R or 0.5 µA, whichever occurs first | |
Stimulus Input Resistance | 3.3 kΩ | |
Maximum Stimulus Input | ±50 V | |
Bridge Bal. Output Resist. | 100 Ω | |
I Monitor Output Resist. | 1 kΩ | |
I Monitor Output Scale Factor | 1V = 50 nA | |
Physical Dimensions | Case Size: 12.5 x 20.3 x 25.4 cm (HxWxD) Probe: 9.5 x 65 mm (D x L) with 1.8 m cable |
|
Power |
100 -130 or 220 -240 V, 50/60 Hz, 20 VA |
|
Probe Handle |
8 x 65 mm (D x L) |
|
Shipping Weight |
4.5 kg |
|
Warranty |
Two years, parts & labor |
Order No. | Model No. | Product Description | USA Price | Order |
---|---|---|---|---|
64-0964 | ESP/W-F10N | E Series Electrode Holder, straight style, fits 1.0 mm capillary, Ag wire | Login | Login |
64-0965 | ESP/W-F12N | E Series Electrode Holder, straight style, fits 1.2 mm capillary | Login | Login |
64-0966 | ESP/W-F15N | E Series Electrode Holder, straight style, fits 1.5 mm capillary | Login | Login |
64-0967 | ESP/W-F20N | E Series Electrode Holder, straight style, fits 2.0 mm capillary | Login | Login |
Customers from Europe and Australia can use the Multi Channel Systems - Online Shop to order Warner products or create quotes.
Order No. | Model No. | Product Description | USA Price | Order |
---|---|---|---|---|
64-0090 | IE-251A | IE-251A Intracellular Electrometer, 110-240 VAC, 50/60 Hz | Login | Login |
Electrode Holders (Purchased Separately) | ||||
64-0964 | ESP/W-F10N | E Series Electrode Holder, straight style, fits 1.0 mm capillary, Ag wire | Login | Login |
64-0965 | ESP/W-F12N | E Series Electrode Holder, straight style, fits 1.2 mm capillary | Login | Login |
64-0966 | ESP/W-F15N | E Series Electrode Holder, straight style, fits 1.5 mm capillary | Login | Login |
64-0967 | ESP/W-F20N | E Series Electrode Holder, straight style, fits 2.0 mm capillary | Login | Login |
Accessories | ||||
460-7032 | BNC-2 | BNC to BNC cable, 2 feet (Pomona) | Login | Login |
460-7013 | BNC-6 | BNC to BNC cable, 6 feet (Pomona) | Login | Login |
Replacement Parts | ||||
64-3072 | Voltage probe handle for OC-725, IE-210, and IE-251 | Login | Login | |
64-0043 | Replacement 2510 headstage for IE-251A | Login | Login |