Specialized Tools for Electrophysiology and Cell Biology Research

(BLM-TC) Planar Lipid Bilayer Thermocycler

Finally, there's temperature control for the bilayer!

The new BLM-TC from Warner Instruments uses Peltier technology to cool, heat or thermocycle a planar lipid bilayer membrane.

  • Peltier driven
  • Cools to 5 °C
  • Heats to 50 °C
  • Heats and cools at 3 °C/min.
  • Stable to 0.2 °C

The BLM-TC from Warner Instruments uses Peltier technology to reliably cool, heat, or thermocycle a planar bilayer membrane.

The tight and reproducible temperature control provided by this unique device can facilitate the measurement of single channel events at physiologic temperatures, or at any temperature between 5 and 50 °C.

The BLM-TC charts temperature at an average rate of 3 °C/min when transitioning between 40 °C to 10 °C. More importantly, this system can maintain the temperature to within 0.2 °C of the set temperature.

Planar Lipid Bilayer Thermocycler (BLM-TC)

The BLM-TC system is comprised of a Peltier-driven bilayer platform (compatible with Warner's SPIN-2 bilayer stirplate and BPS-2 Perfusion), a CL-100 bipolar temperature controller, and a LCS-1 (Thermal Cooling Module).

The purchase of a BCH-M13 or the BCH-M22 (thermally conductive bilayer chambers) and a standard bilayer cup completes the system.

Note: If you will primarily be working at temperatures above ambient, then we recommend using the larger BCH-M22 chamber to reduce the impact of evaporative losses during use.

Planar Lipid Bilayer Thermocycler (BLM-TC)
BLM-TC Platform Specifications
Temperature Range 5 to 50°C via Peltier-device
Dimensions (H x W x D) 2.41 x 7.21 x 9.80 cm (0.95 x 2.84 x 3.86 in)
Cable 2.4 m (8 ft) with 15 pin D connector
Weight 0.34 kg

 

 

LCS-1 Specifications
Pump rate 4201/hr (111 gal/hr)
Power Input Universal Input 100-240 VAC 50/60Hz
Power Output 12 VDC 540 mA
Power Connector Type 9 pin Male 'D'
Physical Dimensions
Chassis Size (D x W x H) 49.5 x 21.3 x 9.5 cm
Weight 3.63 kg (8 lbs)
Chassis material Aluminum
Water Jacket Ports Male thread to1/8' Barb Fittings
Warranty One Year

 

 

 

 

CL-100 Specifications
Maximum Output Voltage ± 15 V DC
Maximum Output Current 2.4 Amps
Maximum Output Power 36 W (8 Ω load)
Manual Voltage Range 0 to ± 15 V
Temperature Range

0 to 50°C via Peltier-device
Ambient to +65°C via resistive heating

Recorder Outputs

Control Temp Out 100 mV/°C
Monitor Temp Out 100 mV/°C

Inputs

Front Panel BNC for external thermistor
Rear Panel BNC for external set temp
Rear Panel BNC for external voltage set
Rear Panel 15 pin Female 'D' Input/Output

Meter
3 1/2 digit LED display
Set Temperature, 0-50°C maximum
Control Temperature
Monitor Temperature
Output Voltage, ± 15 V maximum
Power Requirements 100-130 or 220-240 VAC
50Hz or 60 Hz
80 VA
user selectable
Shipping Weight 5.6 kg
Enclosure Dimensions H x W x D
8.9 cm x 20 cm x 25.4 cm

 

 

Order No. Model No. Product Description USA Price Order
64-0107 TA-29 Cable with bead thermistor Login Login
64-1922 LCS-1 Liquid Cooling System Login Login
64-0352 CL-100 Bipolar temperature controller Login Login
64-1729 BCH-13TH Thumb screw and rubber plug for BCH-M13 and BCH-M22 chambers Login Login

References

  1. Enhanced Excitation-Coupled Calcium Entry in Myotubes Expressing Malignant Hyperthermia Mutation R163C Is Attenuated by Dantrolene 
    Gennady Cherednichenko, Chris W. Ward, Wei Feng, Elaine Cabrales, Luke Michaelson, Montserrat Samso, José R. López, Paul D. Allen, and Isaac N. Pessah 
    Mol Pharmacol. 2008 Apr;73(4):1203-12. Epub 2008 Jan 2.
  2. The Peripheral Benzodiazepine Receptor Modulates Ca2+Transport through the VDAC in Rat Heart Mitochondria 
    Tamse CT, Lu X, Mortel EG, Cabrales E, Feng W, Schaefer S
    Journal of Clinical and Basic Cardiology 2008; 11 (Issue 1-4), 24-29

 

 

Order No. Model No. Product Description USA Price Order
64-1922 LCS-1 Liquid Cooling System Login Login
Accessories and Replacement Parts
64-0107 TA-29 Cable with bead thermistor Login Login
64-0454 BNA48 Ground cable, banana-banana, 48" Login Login
Cup and Chamber Accessories
64-1729 BCH-13TH Thumb screw and rubber plug for BCH-M13 and BCH-M22 chambers Login Login
Cups and Chambers - Classic 13 mm
64-0451 BCH-M13 Bilayer chamber, 1.0 ml working volume, with stirbar, without cuvette Login Login
Cups and Chambers - Classic 22 mm
64-0453 BCH-M22 Bilayer chamber, 3.0 ml working volume, with stirbar, without cuvette Login Login
Optional Items and Accessories
64-0450 BLM-TC Bilayer thermocycler (requires bilayer chamber and cup) Login Login
Temperature Control
64-0352 CL-100 Bipolar temperature controller Login Login

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