Specialized Tools for Electrophysiology and Cell Biology Research

(SIU-102) Bipolar Stimulator

Product Summary

Designed for use with Warner's imaging chambers and dish inserts with field stimulation electrodes.

 

  • Constant Current and Constant Voltage
  • Bipolar, Pulse and DC modes
  • Optical coupling isolates the stimulator from the pulse source
  • Current up to 100 mA
  • Voltage up to 100 V
  • For imaging applications only

The SIU-102 is an ideal unit for providing cell stimulus in an imaging application. Unfortunately, the SIU-102 is not compatible with electrophysiological applications and we recommend using the STG Series, the DS4, or the monopolar DS2A and DS3 for these environments.

This instrument features optical isolation at the input and transformer isolation at the output. Timing pulses can be controlled by any device capable of generating a TTL level positive pulse (for example, a computer with data acquisition). Positive or negative pulses, positive or negative DC, and bipolar pulses are possible, all in constant current or constant voltage delivery modes.

For bipolar delivery, a positive pulse during the input pulse is followed immediately by a negative pulse of equal duration and amplitude. Bipolar pulse widths from 100 µs to 100 per each polarity are possible. Output amplitude is set using a range mode switch in conjunction with a ten-turn potentiometer to set a percentage of the selected range.

General connection to the SIU-102 is via the panel-mounted banana jacks. A CC-102 cable is available for connection of the SIU-102 to stimulating electrodes having 1 mm pins on their ends.

 

Indicator lights keep the user apprised of the following:

High Voltage: Lights red when output voltage above 30 volts.

Compliance: Lights when impedance across output is too high for current setting.

T>100 Sec: Lights when pulse width input is longer than 100 seconds in Bipolar mode.

Ext. Trigger:Lights when a valid input is applied to the Pulse In BNC.

Headstages

(CC-102 Cable)
Output Waveform DC Level, Current Pulse or Voltage Pulse
Output Current Ranges 1, 10, and 100 mA
Output Voltage Ranges 10 and 100 V
Output Impedance Voltage Mode 10 V Range: 1 kΩ 100 V Range: 10 kΩ
Output Compliance 100 V
Output Polarity Selected by Mode Switch Red connector is positive in any positive mode Red connector is negative in any negative mode
Amplitude Control Multi-turn dial
Input Pulse Requirements TTL level, positive pulse 3 volt, 1 mA minimum Minimum Pulse Width: 100 µs Maximum Pulse Width: 100 s (Bipolar Mode Only)
Input Connector BNC
Output Connector Banana Jacks
Power Requirements 90 to 270 VAC, 50/60 Hz, 10 VA
Physical Size,
H x W x D
8.9 x 20 x 25.4 cm
Shipping Weight 3 kg
Warranty Two years, parts and labor
Order No. Model No. Product Description USA Price Order
64-1325 WC1-10 1 mm pin, 10 pack Login Login

References

  1. The age-related decrease in catecholamine sensitivity is mediated by ß1-adrenergic receptors linked to a decrease in adenylate cyclase activity in ventricular myocytes from male Fischer 344 rats 
    Farrell SR, Howlett SE 
    Mech Ageing Dev. 2008 Dec;129(12):735-44
  2. Action spectra of electrochromic voltage-sensitive dyes in an intact excitable tissue 
    Foley J, Muschol M 
    J Biomed Opt. 2008 Nov-Dec;13(6):064015
  3. The homologous rat chromogranin A1–64 (rCGA1–64) modulates myocardial and coronary function in rat heart to counteract adrenergic stimulation indirectly via endothelium-derived nitric oxide 
    Cerra MC, Gallo MP, Angelone T, Quintieri AM, Pulerà E, Filice E, Guérold B, Shooshtarizadeh P, Levi R, Ramella R, Brero A, Boero O, Metz-Boutigue MH, Tota B, Alloatti G
    FASEB J. 2008 Nov;22(11):3992-4004
  4. Endothelium-derived Nitric Oxide mediates the anti-adrenergic effect of Human Vasostatin-1 (CgA 1-76) in rat ventricular myocardium 
    Gallo MP, Levi R, Ramella R, Brero A, Boero O, Tota B, Alloatti G
    Am J Physiol Heart Circ Physiol. 2007 Jun;292(6):H2906-12
  5. Contribution of Calcium Channel Subtypes to the Intracellular Calcium Signal in Sensory Neurons: The Effect of Injury 
    Fuchs A, Rigaud M, Sarantopoulos CD, Filip P, Hogan QH
    Anesthesiology. 2007 Jul;107(1):117-27
  6. The effects of isoproterenol on abnormal electrical and contractile activity and diastolic calcium are attenuated in myocytes from aged Fischer 344 rats 
    Farrell SR, Howlett SE 
    Mech Ageing Dev. 2007 Oct;128(10):566-73
  7. B-Ephrin Reverse Signaling Is Required for NMDA-Independent Long-Term Potentiation of Mossy Fibers in the Hippocampus
    John N. Armstrong, Michael J. Saganich, Nan-Jie Xu, Mark Henkemeyer, Stephen F. Heinemann, and Anis Contractor 
    The Journal of Neuroscience, March 29, 2006 • 26(13):3474 –3481

Customers from Europe and Australia can use the Multi Channel Systems - Online Shop to order Warner products or create quotes.

Order No. Model No. Product Description USA Price Order
64-1424 SIU-102 Bipolar stimulator, high current, non-isolated Login Login
64-1425 CC-102 Cable, BNC + male banana to 1 mm jack (for use with field stimulation chambers) Login Login
Accessories and Replacement Parts
64-1325 WC1-10 1 mm pin, 10 pack Login Login
460-8090 2U Rack handle Login Login

Need support?

Want to know more about our quality products or need assistance in technical support?