Specialized Tools for Electrophysiology and Cell Biology Research

pco.edge 4.2 LT CMOS Camera

Product Summary

The pco.edge 4.2 LT is equipped with an innovative scientific CMOS sensor that provides crisp images and precise measurements

  • 0.8 e- med readout noise
  • 2048 x 2048 pixel resolution
  • 37500 : 1 dynamic range
  • 40 fps maximum frame rate
  • up to 82 % quantum efficiency
  • USB 3.0 interface


Groundbreaking sCMOS technology for outstanding image quality

Pco.edge 4.2 LT CMOS Camera
Pco.edge 4.2 LT CMOS Camera
Pco.edge 4.2 LT CMOS Camera

superior image quality

The pco.edge sCMOS camera features outstanding low read out noise.

Even at maximum speed of 40 frames/s at full resolution of 2048 x 2048 pixel the noise is 0.8 e- (med). Moreover the pco.edge provides an excellent homogeneous pixel response to light (PRNU, photo response non-uniformity) and an excellent homogeneous dark signal pixel behaviour (DSNU,dark signal non-uniformity) which is achieved by a sophisticated electronic circuit technology and firmware algorithms.

rolling shutter readout modes

pco.edge sCMOS cameras featuere a variety of precise synchronization modes which are optimized for advanced microscopy imaging and scanning.

The flexible frame and line triggers with very low latency and, in combination with the free selectable readout modes, can easily be combined to cover every modern microscopy situation

For example, one mode is used in a lightsheet or SPIM application, the lower right rolling shutter operational mode “single top down” operation is convenient to properly synchronize the camera exposure with the scanner. On the other hand, if speed is required and a ?ash like exposure is applied the upper left mode “dual outside in” is used for localization microscopy techniques like GSD, PALM or STORM.

flexibility and free of latency

rolling shutter readout modes

User selectable choice of rolling shutter modes for exposure provides fexibility for a wide range of applications.

The advantages of rolling shutter are high frame rates and low read out noise. Due to realtime transmission of the image data to the PC, there is no latency between recording and access or storage of the data.

37500:1 dynamic range

Due to the excellent low noise and the high fullwell capacity of the sCMOS image sensor an intra scene dynamic range of better than 37500:1 is achieved.

A unique architecture of dual column level amplifers and dual 11 bit ADCs is designed to maximize dynamic range and to minimize read out noise simultaneously. Both ADC values are analyzed and merged into one high dynamic 16 bit value.

Pco.edge 4.2 LT CMOS Camera
pco.edge 4.2 LT
image sensor
type of sensor scientifc CMOS (sCMOS)
image sensor CIS2020A
resolution (H x V) 2048 x 2048 active pixel
pixel size (H x V) 6.5 x 6.5 µm
sensor format /diagonal 13.3 x 13.3 mm /18.8 mm
shutter modes rolling shutter (RS) - with selectable readout modes
global reset (GR) - with rolling readout
MTF 76.9 lp/mm (theoretical)
fullwell capacity (typ) 30,000 e-
readout noise 0.8 med /1.3 rms e-
dynamic range (typ.) 37,500:1 (91.5 dB)
quantum efficiency up to 82% @ peak
spectral range 370 - 1100 nm
dark current (typ) < 0.8 e- /pixel /s @ 10°C
DSNU < 0.3 e- rms
PRNU < 0.2%
anti blooming factor > 10,000
frame rate 40 fps @ 2048 x 2048 pixel
exposure / shutter time RS: 100 µs - 10 s
GR: 30 µs - 2 s
A/D dynamic range 16 bit
A/D conversion factor 0.46 e- /count
pixel scan rate 110.0 MHz
pixel data rate 220.0 Mpixel/s
binning horizontal x1, x2, x4
binning vertical x1, x2, x4
region of interest (ROI) horizontal: 4 pixel steps
vertical: 1 pixel steps
non-linearity < 0.6%
cooling method +10 °C stabilized
peltier with fan forced air, up to 27 °C ambient
trigger input signals frame trigger, programmable input with SMA connectors
trigger output signals exposure, busy, line, programmable output with SMA connectors
data interface USB 3.0
time stamp in image (1 us resolution)
power supply 12-24 VDC (± 10%)
power consumption 21 W max. (typ. 12 W @ 20 °C)
weight 900 g
operating temperature 10-40 °C
operating humidity range 10-80% (non-condensing)
storage temperature range -10 - 60 °C
optical interface F-mount
CE / FCC certified yes



frame rate table
2048 x 2048 40 fps
2048 x 1024 80 fps
2048 x 512 160 fps
2048 x 256 315 fps
2048 x 128 610 fps
1920 x 1080 76 fps
1600 x 1200 69 fps
1280 x 1024 80 fps
640 x 480 170 fps
320 x 240 335 fps





Click to enlarge

Pco.edge 4.2 LT CMOS Camera

Customers from Europe and Australia can use the Multi Channel Systems - Online Shop to order Warner products or create quotes.

Order No. Model No. Product Description USA Price Order
69-3132 Edge 4.2 LT PCO Edge 4.2 LT, CMΩS camera Login Login

Need support?

Want to know more about our quality products or need assistance in technical support?